Arena also singled out PSV Eindhoven midfielder DaMarcus Beasley - alongside Donovan one of his most important players - for strong criticism.
"We got nothing out of Beasley on the night," Arena said.
"Not enough players took the initiative. We didn't get too many good performances."
Although known for his generally blunt style, Arena was in top form as he rattled off his team's failings with refreshing candor.
"A number of players played poorly," he said. "Aside from giving up the early goal, second balls were a big part of the game and they won more than their fair share."
