Yes, Jonathan Spector (U.S. U23) played for Manchester United and currently plays for West Ham United. He was selected to play for the East Team in the 2003 McDonald's All-American High School Soccer Game at Blackbaud Stadium on Daniel Island, SC, but I don't remember him playing.
However, Arsenal youth-signee Danny Karbassiyoon (who has since been released and is now a scout for the Gunners), Corey Ashe (Houston-MLS/UNC), Billy Chiles (U23/Towson)), Adam Cristman (U23/New England-MLS), Jon Eggert (South Carolina), Kyle Helton (Virginia), Phil Marfuggi (Clemson), and Olatomiwa Ogunsola (Clemson), to name a few, all suited up for the East Team. The West Team featured Kenny Cooper (SMU/FC Dallas), Patrick Ianni (UCLA/Houston-MLS), and Jamie Watson (North Carolina) played as well. J.L. Mann HS boys soccer coach William Hosea served as a Co-Coach for the squad.