Actually, I believe Hammond was the #1 seed going into the playoffs for the upperstate in 2008. St Joseph's, upset Hammond at Hammond in the semis, after playing HHC in the first round in probably an away but neutral site.

2008 was Upper: Hammond, CN, St. Joseph's, Ben Lippen
2008 was Lower: Pinewood, HHC, PG, Northwood

New region alignment with a 3rd region has this up in the air at the moment. I'm sure someone knows, but it's not public yet that I know of.