According to the South Carolina High School League website (and I'm sure this is incomplete/unofficial), three girls have scored at least 100 goals in their South Carolina high school careers:

Bryn Post (RNE), 2002 = 220
Liz Speights (Wando), 1996 = 148
Claire Wigfall (Wando), 2001 = 141

Tonight, at home against Lancaster, Fort Mill's Danielle Schmitt will attempt to join this elite group. Danielle is currently at 97.