Women's bodies transform pretty dramatically in order to endure childbirth; one would imagine that other monthly shifts would be nearly as powerful.
I would suspect that hormone meds would tend to fall well below the normal shifts—though I don't know for sure—And simply taking hormone meds may not replicate the full set of changes that occur during the time we shall not name.
A great study would be female hormone therapy on MEN—to see if the risk increases. Maybe some on this discussion board could volunteer. . .
