Last year in 3A, Region III (Dreher and AC Flora were tied with same region records) the tie-breaker was:
1. head to head (which was split)
2. goal differential in the two head to heads (which was even)
3. goal differential (max of 3) amongst other region results, which Dreher had the better of.

Thus Dreher was the #1 seed from Region 3 last year.

I think after tie-breaker #3 it went to a coin flip. It never did go to an out-of-region record.