Here's a quick list of my "top players" from the Palmetto State over the past 25 years. Some have gone on to professional careers, but many did not have that opportunity until the past 10 or so years. I'm not commenting on any current high school players.
Jason Alsberry (West Florence), Forward, ???, just from a soccer talent standpoint this guy was simply great at finishing scoring chances
Marty Baltzegar (Irmo), Defender, University of South Carolina
NSCAA All-American -- one of only two national collegiate All-Americans from this state
Scott Brown (Irmo), Defender, University of South Carolina -- solid marking back at the collegiate level and hard-nosed player
Steven Busch (Myrtle Beach), Forward, German exchange student (no one had an answer defensively for this goal machine who scored 85 goals in 2000)
Doug Campbell (Middleton), Goalkeeper, ??? -- maybe the College of Charleston (can't remember)
Tomek Charowski (Christ Church), Midfielder, Duke University, well known player at the national level from club soccer and led the Cavaliers to four-straight 1A titles despite missing a lot of his senior season due to other soccer commitments
Andrew Coggins (Middleon), Forward, University of South Carolina, one of the top players ever from S.C. and I think the best ever when discussing winning balls in the air and scoring off headers
Craig Forest (Irmo), Forward, Wofford College/University of North Carolina-Charlotte -- paired with Harriford up top for the Yellow Jackets and was part of a lethal and physical scoring duo, All Metro Conference at UNCC
Ward Harriford (Irmo), Forward, University of South Carolina -- bad knees cost him a promising career
Kyle Izzard (Andrew Jackson), Forward, ??? (a great high school goal scorer)
Johnnie Keen (Chapin), Forward/Midfielder, The Citadel -- if you could catch him you had a chance to contain him, but not much
Ryan Kurtz (Irmo), Forward, University of South Carolina/College of Charleston
Andy Kwon (Spring Valley), Midfielder, Duke University
Troy Lesesne (Brookland-Cayce), Midfielder, College of Charleston
NSCAA All-American (see Baltzegar above), not a harder worker in this group
J.C. Nicholson (T.L. Hanna), Midfielder/Defender, gritty player who maxed out his potential and was a stalwart at the high school level and very solid collegian
Erik Ozimek (Spring Valley), Midfielder, University of Maryland/Davidson College
Michael Pao (Riverside), Forward, Vanderbilt University
Jeremy Ransom (Chapin), Goalkeeper, Presbyterian College, NCAA Division II All-American, played professionally for a while with Hershey (PA)
Jabari Seabrook (Brookland-Cayce), Defender, College of Charleston, a super marking back with unbelievable speed and the strongest player I've ever seen at 5-6, 140 pounds
Jorn Steinmoen (Brookland-Cayce), Midfielder, Norwegian exchange student (unbelievable year in '89 with 75 PTS, 29 G, 17 A and at 6-4, 190-pounds was a man amongst boys)
Temoc Suarez (Bishop England), Midfielder, University of North Carolina, probably gets my vote for the best player I've seen from S.C.
Glenn Thompson (Irmo), Goalkeeper, University of South Carolina, "old school" GK who was the best of his time in S.C. of the early 1980s
Adam Walker (Bishop England), Defender/Utility, University of Kentucky, can play this guy anywhere on the field
Hans Whetstone (Brookland-Cayce), Utility, University of South Carolina, blue collar player that was tough as nails, Team Captain at USC
Honorable Mention -- a bunch of the "best teams" from Greenwood (mid 90s), Mauldin(80s and 90s), North Augusta (87-90), Wando (1980-present), etc., that had great players for the high school level and posted great records due to their talent and depth ... I'm sure some upper state and lower state folks can contribute more about the teams from Riverside of the late 80s/early 90s and some more of the Bishop England and Middleton teams of the same era.